Early Infarct Growth Correlates With Both Collateral Status and Clinical Outcomes After Thrombecomy

Background: We assessed the correlation between early infarct growth rate (EIGR), collaterals and clinical outcomes following endovascular thrombectomy (EVT). Methods: In a prospective multicenter cohort study of imaging selection for EVT (SELECT), consecutive patients with large vessel occlusion (ICA, M1, M2) presenting up to 24 hr from last known well (LKW) were enrolled at 9 centers. CT perfusion was obtained prior to EVT. EIGR was defined as CTP ischemic core volume (rCBF 2. Results: Of 445 enrolled, 284 received EVT. The optimal EIGR was u003c10 ml/hr; 199 were slow and 85 fast progressors. Fast progressors had higher median NIHSS (19 v...