P189 Role of digestive wall’s ultrasound in the evaluation of post-surgical recurrence in Crohn's disease: correlation with endoscopic findings

JOURNAL OF CROHNS & COLITIS(2019)

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摘要
Endoscopy remains the examination of choice in the evaluation of activity in Crohn's Disease (CD) after surgery (ADC-AS). However, digestive wall’s ultrasound (US-DW) may represent a non-invasive alternative. The objective of this study was to determine the diagnostic accuracy and concordance of this modality comparatively to endoscopy. Cross-sectional study, comprising a period of 14 months, carried out in patients with established CD and ileocaecal resection due to the disease. Performed US-DW (HI-VISION avius®, Tokyo, Japan) with linear probe B-mode/Doppler prior to ileocolonoscopy. US-DW and colonoscopy were performed on the same day by 2 specialists in gastroenterology dedicated to ultrasound and inflammatory bowel disease, in a double-blind mode. Collected demographic and clinical data [Harvey–Bradshaw index (HBI, remission: ≤4)], serological/faecal inflammatory parameters [leucocytes (4 < N <10 × 109 cells/l), C-reactive protein (≤0.5 mg/dl) faecal calprotectin (N <50 mg/kg), endoscopic (score Rutgeerts: remission < i2) and ultrasound [intestinal wall thickening (N ≤ 3 mm) and digestive wall’s vascularisation using the semi-quantitative score of Limberg (absent = 0, sparse = 1; moderate = 2; marked = 3)]. Included 39 patients (female: 64.1%, mean age: 43.5 ± 15.3 years). Surgery performed, on average, 5.3 ± 5.3 years after diagnosis. Mean post-surgery follow-up: 9.9 ± 6.9 years. Montreal classification: L1 61.5% (n = 24), L3 38.5% (n = 15), B1 and B2 28.2% (n = 11) and B3 43.6% (n = 17). Most of patients were in clinical remission (87.2%; n = 34) with mean HBI 2.1 ± 2.2. Twenty-two patients (56.4%) have normal inflammatory markers. US-DW (intestinal wall thickening> 3 mm and/or Limberg> 1) was abnormal in 61.5% (n = 24). Endoscopic remission (Rutgeerts
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关键词
crohn,ultrasound,digestive walls,endoscopic findings,post-surgical
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