Non-food bioactive products: Semisynthesis, biological activities, and mechanisms of action of oximinoether derivatives of matrine from Sophora flavescens

•Five compounds display potent insecticidal activity against Mythimna separata.•Two compounds exhibit > 6 folds more pronounced acaricidal activity than matrine.•nAChR α1, α2, α4 and β3 subunits may be the target of action of 7b against Tetranychus cinnabarinus.