TM1-6 Intramedullary spinal cord tumours – a single centre 10 year retrospective review

Journal of Neurology, Neurosurgery, and Psychiatry(2019)

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Abstract
Objectives To identify clinically relevant predictors of progression free survival by retrospectively analysing the anatomical location, pre- and post-operative function and histology in intramedullary spinal cord tumours from a single neurosurgical centre over 10 years. Design Retrospective review. Methods 49 patients were identified from a surgical database. Variables collected included pre-and post-operative Frankel Grade and Modified McCormick Scale assessments, tumour histology, extent of resection and length of follow up. Chi-Squared, Kaplan-Mier Survival and Mann-Whitney U-Tests were completed. Results There was a statistically significant relationship between identification of the tumour plane and extent of resection (p Conclusions Tumour plane and the extent of tumour resection are significant determinants of progression free survival. Ependymoma, whilst being the commonest histology in our series were also the most resectable. Whilst complete resection reduces the rate of recurrence, tumour grade is the most important predictor of outcome.
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