Proceedings #48: Long-term Transcranial Direct Current Stimulation Treatment Paired with Adaptive Cognitive Training Leads to Clinical Benefit

Introduction: Transcranial direct current stimulation (tDCS) is a safe and well-tolerated form of noninvasive brain stimulation that delivers a low amplitude (1 – 4 mA) direct current through scalp electrodes. Cognitive impairment is a common and often disabling symptom of multiple sclerosis (MS) which has been shown to improve with cognitive training paired with tDCS. Here we compared the benefits of tDCS paired with either adaptive cognitive training (aCT) or non-adaptive cognitive training (nCT). To provide the extended treatment sessions needed for cognitive training, we administered tDCS to patients in their homes using our remotely supervised or RS-tDCS protocol.