Abstract 19003: Long-term Outcomes After Subcutaneous Defibrillator Implantation in Patients With a Previous Device Infection

Introduction: Long-term outcomes for S-ICD reimplantation after a prior CIED infection are unknown. Hypothesis: S-ICD infection and death are not increased in those with a prior CIED infection. Methods: This was a single center retrospective study of patients undergoing S-ICD implantation from 2010 to 2016, comparing those had a prior CIED infection requiring extraction to those without a prior infection. The primary composite outcome was death and S-ICD infection. Survival analysis was performed with Kaplan Meier curves, log-rank tests, and Cox regression. Results: 174 patients were included, 28 with a prior CIED infection and 146 without a prior infection. Follow-up was similar for those with and without (median 21 months, IQR 11-41; p-value 0.11) a prior CIED infection. Those with a prior infection were older (60 years; 95% CI 54-65 vs 52 years; 95% CI 50-55; p-value 0.03), but the groups were similar regarding gender (71% male; p-value 0.35), EF (37%; 95% CI 35-40; p-value 0.76), ICD indication (29% s...