One step DNA amplification of mammalian cells in picoliter microwell arrays
RSC ADVANCES（2019）
Abstract
We developed a strategy for direct DNA amplification of single cells on a PEG-modified silica chip with 30 600 picoliter-sized microwells. HPV-positive cells in heterogeneous populations were successfully detected with high accuracy sensitivity as high as single copy.
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Key words
picoliter microwell arrays,step dna amplification,mammalian cells
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