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Nodal Dynamics After In Vivo Rescue Of Beta Iv Spectrin Expression

The Journal of Neuroscience(2019)

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Abstract
Precise localization of voltage-gated sodium channels (Nav) at nodes of Ranvier is required for efficient signal transmission along myelinated axons. By restricting Nav to gaps in the myelin sheath, the nodal complex focuses the regeneration of action potentials to discrete sites and ensures
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