The Nationwide Danish Caucerbiobank: Future Possibilies.

e22196 Background: Through Danish CancerBiobank (DCB) to ensure collection of blood and tissues optimal for translational research from all patients diagnosed with primary cancer. Methods: The infrastructure was established through the Departments of Pathology and Departments of Clinical Biochemistry at the six University hospitals in Denmark. All departments agreed on national technical recommendations. A national on-line database was established to registry information such as pre-analytical factors, laboratory procedures and verification of the diagnosis of the colleted tissues. The database is linked to the national pathology register (www.patobank.dk) and the data can be combined with Danish clinical databases and other registers relevant for research. Results: DGC was implemented in January 2010. In 2012 biological materials from 9.609 patients have been collected, a total of 11.121 blood samples and 6.814 tissue samples equivalent to a 30% coverage of all patients with primary cancer. From 3.056 tissue samples a corresponding blood sample was collected. A twofold increase of material collected is observed from 2010 to 2012. Today DCB is responsible for collecting biological materials for 35 research projects. Conclusions: The DCB is unique nationally and internationally, due to: 1) National recommendations for handling of biological materials 2) Centralized nationwide data registration 3) Information of both blood and tissue for the single patient 4) Connection to the final diagnosis through Patobanken and 5) Connection to the nationwide clinical databases and other national registries. The success for DCB will be translational research results of clinical importance for cancer patients.