Microglia and the Purinergic Signaling System

Stefano Calovi,Paula Mut-Arbona,Beáta Sperlágh

Neuroscience（2019）

引用 82|浏览31

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摘要

•ATP is released as a signaling molecule, or as a danger signal to the extracellular space in the brain.•P2X and P2Y receptors modulate microglia pro- or anti-inflammatory phenotypical shift.•Purinergic signaling dynamically control microglia physiological activity according to the context.

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关键词

AD,ADP,AMP,ATP,CNS,LPS,NO,P2X(*)R,P2Y(*)R,Panx1,PD,ROCK,ROS,TPM,UDP

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