Methemoglobinemia as a biomarker of dapsone-induced mania severity

Romain Colle,Abd El Kader Ait Tayeb,Pierre Mesdom, Mathilde de Menthon,Laurent Becquemont,Céline Verstuyft,Denis J. David,Olivier Lambotte,Emmanuelle Corruble

Journal of Affective Disorders（2019）

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摘要

•Dapsone-induced mania severity is correlated with methemoglobinemia.•Dapsone could induce mania by enhancing oxidative stress.•Methemoglobinemia could be a proxy of oxidative stress during dapsone treatment.

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关键词

Dapsone,Mania,Methemoglobinemia,Oxydative stress,Biomarker

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