Chrome Extension
WeChat Mini Program
Use on ChatGLM

A novel technical extension of the Forced Oscillation Technique

EUROPEAN RESPIRATORY JOURNAL(2018)

Cited 0|Views22
No score
Abstract
This work introduces a novel technical extension of the Forced Oscillation Technique (FOT) by measuring the respiratory impedance over the whole lung volume at different frequencies. This method proposes a new measurement protocol in which patients breathe slowly from residual volume to total lung capacity, while oscillations are applied simultaneously on the spontaneous breathing. The respiratory impedance Z, computed by means of the windowed cosine fitting method, is frequency- and volume-dependent. The impedance-volume diagram was introduced as a diagnostic tool for abnormalities in lung mechanics. Data were obtained from healthy volunteers and volunteers with mild asthma. The volume-dependency of the respiratory impedance could be clearly observed in all data. In healthy subject, the respiratory resistance (the real part of Z) was maximum at the lowest lung volume and decreases at higher lung level, while the respiratory reactance (the imaginary part of Z) remain constant over a wide range of lung volume. Least-squares parameter estimation was performed on the data for the extended-RIC and the constant-phase models. As a result, both models failed in describing the volume-dependency of Z. Two new extended models were proposed for a better fit of the data: the volume-dependent extended-RIC and the volume-dependent Mead’s models. Overall, the volume-dependent Mead’s model yielded the smallest estimation error. Fig 1: The impedance-volume diagram
More
Translated text
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined