One‐step Electrodeposition of Tris(hydroxymethyl) Aminomethane – Prussian Blue on Screen‐printed Electrode for Highly Efficient Detection of Glycosylated Hemoglobin
ELECTROANALYSIS(2019)
Abstract
In this work, the modified Prussian blue (PB) film showed more stable performance in alkaline solution by one-step electrodepositon of PB with tris(hydroxymethyl) aminomethane (Tris) on screen-printed electrode (SPE). The morphology and structure of the modified Tris-PB/SPE was characterized by scanning electronic microscopy, infra spectroscopy, Raman spectroscopy and X-ray diffraction. It was inferred that the Tris particles embedded in the PB deposit layer resulted in the change of PB structure and improve its stability in alkaline solution. And then, the modified Tris-PB/SPE was applied in the detection of Glycosylated hemoglobin (HbA1c). The optimum experimental conditions are pH 7.5, 100 mV/s, 4 mu L FAOD and 5 min reaction time. The linearship of HbA1c is i=22.90 C+101.9 in the range of 0.1-2 mmol/L. Comparing with PB/SPE, Tris-PB/SPE shows better sensitivity and recovery.
MoreTranslated text
Key words
Prussian blue,tris(hydroxymethyl) aminomethane,screen-printed electrode,diabetes,glycosylated hemoglobin
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined