Bioassay-guided isolation of anti-inflammatory O-sulfated withanolides from Acnistus arborescens (Solanaceae)

Clara Steinbrueck,Nohelia Mora-Ugalde,Carlos Morales, Randall Loiaza,Alfonso J. García-Piñeres,Juan J. Araya

Phytochemistry Letters（2019）

引用 4|浏览10

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摘要

•Bioassay-guided fractionation of Acnistus arborescens organic extract.•Isolation and identification of two O-sulfated withanolides from polar fraction.•Compounds showed NO inhibition in LPS-stimulated murine macrophage assay.

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关键词

Acnistus arborescens,Anti-inlammatory,Sulfated withanolides,Cytotoxicity

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