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Abstract 12867: The Mechanism of K-877, a Highly Potent and Selective Pparalpha Modulator, on Regulation of Synthesis, Secretion and Metabolism of Triglycerides and Cholesterol

Toshiaki Takizawa, Yuta Inokuchi,Shinji Goto,Yasunobu Yoshinaka,Kazutoyo Abe,Keisuke Inoue,Sohei Tanabe

Circulation（2013）

Cited 23|Views6
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Abstract
Introduction: Triglycerides (TG) are one of the important risk factors for cardiovascular diseases. TG are synthesized via fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC), and hydrolyzed...
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Key words
Ppar, Lipases, Hyperlipidemia, Pharmacology, Cholesterol-lowering drugs
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