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Controlling SpyTag/SpyCatcher Reactivity via Redox-Gated Conformational Restriction

Wen-Hao Wu,Jingjing Wei,Wen-Bin Zhang

ACS Macro Letters（2018）

Cited 10|Views21
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Abstract
Herein, we report that the reactivity of genetically encoded SpyTag/SpyCatcher chemistry can be manipulated via redox-gated conformational restriction, which facilitates the preparation of all-protein-based hydrogel with latent reactive sites for subsequent covalent functionalization.
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spytag/spycatcher reactivity,redox-gated
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