Vitamin D And Risk Of Pregnancy-Related Hypertensive Disorders: Mendelian Randomization Study

Maria C. Magnus,Kozeta Miliku,Anna Bauer,Stephanie M. Engel,Janine F. Felix,Vincent W. V. Jaddoe,Debbie A. Lawlor,Stephanie J. London,Per Magnus,Ralph McGinnis,Wenche Nystad,Christian M. Page,Fernando Rivadeneira,Lars C. Stene,German Tapia,Nicholas Williams,Carolina Bonilla,Abigail Fraser

OBSTETRICAL & GYNECOLOGICAL SURVEY（2018）

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摘要

(Abstracted from BMJ 2018;361:k2167) Observational studies have found that women with lower levels of 25-hydroxyvitamin D are at greater risk of preeclampsia. Although some small trials of vitamin D supplementation in pregnancy have suggested a potential benefit of supplementation, a recent meta-analysis found no impact on preeclampsia from vitamin D supplementation.

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关键词

Mendelian randomization,Vitamin D and neurology,Pregnancy,Internal medicine,Medicine

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