Comment on “Coordination‐Driven Self‐Assembly of a Molecular Knot Comprising Sixteen Crossings”

The remarkable metalla-knot obtained by Kim, Jung, Chi and colleagues is an 8 knot, a metalla-knot that comprises eight crossings, not sixteen. It is the first knot to be synthesized having the 8 topology. Like several previous molecular knots, it adopts a conformation that does not correspond to the reduced form of the knot and has additional persistent nugatory crossings.