A critical appraisal of the measurement of serum ‘cholesterol efflux capacity’ and its use as surrogate marker of risk of cardiovascular disease

Malcolm Anastasius,Celine Luquain-Costaz,Maaike Kockx,Wendy Jessup,Leonard Kritharides

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids（2018）

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摘要

The ‘cholesterol efflux capacity (CEC)’ assay is a simple in vitro measure of the capacities of individual sera to promote the first step of the reverse cholesterol transport pathway, the delivery of cellular cholesterol to plasma HDL.

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apoA-I,apoB,apoE,ABCA1,ABCG1,ACAT,ATP,CAD,CAC,cAMP,CE,CETP,CEC,CT,CVD,CLA-1,FC,FH,HDL,HDL-C,HMDM,hsCRP,LCAT,LDL,LDLR,LXR,MI,NCEH,PEG,PL,PLTP,PPAR,RCT,RNA,RXR,SR-BI,STEMI,VLDL

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