Loading and release of the complex [Pt(DTBTA)(DMSO)Cl]Cl·CHCl3 with the 2,2′-dithiobis(benzothiazole) ligand into mesoporous silica and studies of antiproliferative activity on MCF-7 cells

Polyhedron(2018)

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摘要
Complex(1) was encapsulated on MCM41 and MCM41-NH2 mesoporous silica. The mechanism of anchoring of MCM41-NH2 on the complex(1) was reported. Study of release was performed by using UV–Vis spectroscopy. The complex(1)-conjugates were evaluated by MTT assay and cytofluorimetric assay.
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TEOS,CTAB,APTES,BTA,MTT,DMSO,PI,FACS,FBS,MTT,PBS,PS,RPMI
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