PREDIÇÃO DE TOXICIDADE DOS ESTABILIZANTES USUAIS EM PROPELENTES À BASE DE NITROCELULOSE E DE SEUS PRINCIPAIS PRODUTOS DE DEGRADAÇÃO

This work aims to establish a hierarchy of risks of the stabilizers used in nitrocellulose-based propellants concerning to toxicity, carcinogenicity and mutagenicity. Four stabilizers diphenylamine, ethyl centralite, akardite-II and 2-nitrodiphenylamine and their products of degradation were investigated. The prediction of the toxicity was based on the analysis of their structures with the software Lazar, using the OpenTox framework. Our results provide a quantitative reference of the risks involved in the manufacturing and disposal of propellants due to the use of such stabilizers.