Stereoselective synthesis of C12–C21 common fragment of thermolides 1–5

Tetrahedron Letters(2018)

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摘要
A highly stereoselective synthesis of C12–C21 common fragment of thermolides 1–5 has been described. The salient features of the synthesis are the utilization of desymmetrization protocol, Barton-McCombie reaction, Brown’s asymmetric allylation and Wacker oxidation.
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关键词
Nematodes,Desymmetrization,Barton-McCombie reaction,Brown’s allylation,Wacker oxidation
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