P049 HYPERCALCEMIA DUE TO ISOLATED ELEVATION OF 1,25-DIHYDROXYVITAMIN D IN A PATIENT WITH CROHN’S DISEASE: CASE REPORT AND REVIEW OF LITERATURE

Hypercalcemia has been described in patients with many granulomatous diseases. Elevated serum calcium levels in the setting of granulomatous disease are caused by unregulated production of 1,25-dihydroxyvitamin D by activated macrophages. More commonly, Crohn’s disease is associated with hypocalcemia caused by vitamin D deficiency resulting from ileal resection and malabsorption of fat-soluble vitamins. Here we present a case of sever hypercalcemia in a patient with Crohn’s disease secondary to elevated 1,25-Dihydroxyvitamin D.