МАГНИТНО-РЕЗОНАНСНАЯ ТОМОГРАФИЯ СЕРДЦА В ДИФФЕРЕНЦИАЛЬНОЙ ДИАГНОСТИКЕ ОСТРОГО КОРОНАРНОГО СИНДРОМА У БОЛЬНЫХ НЕОБСТРУКТИВНЫМ КОРОНАРНЫМ АТЕРОСКЛЕРОЗОМ
Russian Journal of Cardiology(2017)
Abstract
Aim. To investigate on the nosological structure of acute coronary syndrome (ACS) in patients with non-obstruction coronary atherosclerosis (NOCA) before and after magnetic resonance imaging (MRI) of the heart. Material and methods . A non-randomized, open, controlled study (NCT02655718). The patients included, with ACS, older than 18 y.o., with NOCA (intact coronary arteries or stenosis ≤50%) confirmed by invasive coronary arteriography (ICAG). Patients with previous revascularization were not included. Results. In the year 2016, to emergency cardiology department (ECD) 913 ACS patients admitted. In 44 (4,8%) the NOCA was found. Mean age 54±10,4 y.o., males 68%, and the groups with ACS with ST elevation (STEACS) and none (NSTEANS) were comparable by clinical and anamnestic parameters. Intact coronary arteries were visualized in 16 (53%), non-significant coronary atherosclerosis was diagnosed in 14 (32%), slower coronary flow — 22 (73%). By MRI with contrast, performed in 11±8 days (2-43 days) from ACS beginning, myocardial oedema was found in 18 (41%), hyperemia in 13 (30%) and fibrosis in 40 (91%); there were no changes in 1 patient. Nosological structure of ACS in NOCA after MRI has been represented: by acute myocardial infarction (MI) in 24 (55%) cases, unstable angina (UA) — in 6 (14%), pseudocoronary myocarditis in 10 (23%), acute aorta dissection in 1 (2%), posttraumatic atherosclerosis in 1 (2%), congenital valve defect in 1 (2%), manifested Wolf-Parkinson-White (WPW) — in 1 (2%). In-hospital mortality was 2%. In comparison of ACS before and post MRI there was significant increase number of patients with myocarditis, by 20%. Conclusion. The prevalence of ACS in NOCA is 4,8%, that is comparable to literature data. Patients with ACS and NOCA are heterogenic group with MI, UA, myocarditis, acute aorta dissection, posttraumatic atherosclerosis, congenital defects, WPW syndrome. In-hospital mortality was 2%. Comparing the structure of the diagnoses before and after MRI, there was significant increase of myocarditis patients number. A high accuracy of MRI was found for differential diagnostics of ACS in NOCA, which was 78%.
MoreTranslated text
Key words
acute coronary syndrome,cardiac magnetic resonance imaging,magnetic resonance imaging,differential diagnostics,non-obstruction
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined