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Disruption Of Circadian Rhythm Function And Anti-Oxidation Via Sirt1-Bmal1 Pathway In 6-Ohda Induced Parkinson'S Disease Model

Yali Wang,Siyue Li,Chun-Feng Liu

JOURNAL OF THE NEUROLOGICAL SCIENCES（2016）

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Abstract
Background: The altered expression of clock genes and disturbance of circadian rhythm are reported in the animal models and patients with PD. And the dysfunction of anti-oxidative system is important pathology mechanism of Parkinson’s disease.
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Key words
circadian rhythm function,parkinsons disease,anti-oxidation
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