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Investigation Of Clinical And Pathological Features Of "Sporadic Creutzfeldt-Jakob Disease" With History Of Neurosurgery To Identify Iatrogenic Cases

T. Hamaguchi,K. Sakai,A. Kobayashi,T. Kitamoto,R. Ae,Y. Nakamura,N. Sanjo,K. Arai, M. Koide, F. Katada,T. Tsukamoto,H. Mizusawa, M. Yamada

JOURNAL OF THE NEUROLOGICAL SCIENCES（2017）

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Abstract
Background: Kuru plaque and type i protease-resistant prion protein (PrP) in Creutzfeldt-Jakob disease (CJD) patients with methionine homozygosity at codon 129 of PrP gene (129MM), denoted as CJD-MMiK, are halmarks to identify acquired CJD cases caused by transmission of the V2 sporadic CJD (sCJD) strain to individuals with 129MM.
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Key words
neurosurgery,disease”,pathological features,creutzfeldt-jakob
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