GW28-e1090 Astragaloside IV Ameliorates Obesity-Associated Hypertension by Up-Regulating α7 Nicotinic Acetylcholine Receptor

Xiao Li,Dufang Ma,Xue Wang,Yongcheng Wang,Jinlong Yang,Ping Jiang

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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摘要

Nicotine, as a non-selective agonist of α7 nicotinic acetylcholine receptor (α7nAChR), has been shown to possess anti-obesity and anti-hypertension properties; however, it is not applicable due to its adverse effects. We tested the hypothesis that Astragaloside IV (As IV), known to counteract

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hypertension,obesity-associated,up-regulating

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