(1232) – Elevated Serum BAFF Levels Are Associated with an Increased Risk of Acute Rejection in Lung Recipients

Acute allograft rejection is a problem in lung transplantation. More than a third of lung transplant recipients are treated for acute rejection in the first year after transplant. Growing evidence suggests that B cells may play a role in allograft rejection in solid organ transplantation. B cell activating factor, BAFF, plays a role in B cell survival, maturation and activation. To date, little is known of the role of BAFF in lung transplantation. We aimed to determine whether there was a correlation between BAFF concentration and acute rejection.