Short-Term Use Of Phenobarbital In The Treatment Of "Superwarfarin" Poisoning.

Background: “Superwarfarin” was developed in the 1970s as an anticoagulant rodenticide. The half-life of the “superwarfarin”, brodifacoum, is four times longer than warfarin. Patients with significant brodifacoum ingestions have often required long-term treatment with vitamin K1 (e.g., 6 months), occasionally with adjunctive phenobarbital therapy.