Clinical Differences Among Hispanics And Non-Hispanic Whites With Colorectal Cancer: A Single Institution'S Experience Over 20 Years.

e14512 Background: Hispanics (H) are the largest and fastest growing ethnic group in the US. With most of the studies focusing in African Americans and Non-Hispanics whites (NHW), defining the characteristics of colorectal cancer (CRC) in the Hispanic population has been a challenge. The aim of our study was to compare the clinico-pathological characteristics and survival among H and NHW with CRC. Methods: We reviewed the records of all patients (pts) diagnosed with CRC at our institution from 1993 to 2013. A total of 2146 pts were studied. Demographics, tumor characteristics, and survival were analyzed. Kaplan-Meier and Cox regression were used for survival and multivariate analysis. Results: There were 318 H and 1828 NHW. Median age at diagnosis was 63 years in H and 70 years in NHW. A significant difference was found in the stage IV pts, with a median age of 60 years for H and 71 years for NHW. Adenocarcinoma was the most common histologic subtype for both groups. At diagnosis, 96 (30%) of H had stage ...