Reproducibility of intermittent theta-burst, paired-pulse, and single-pulse transcranial magnetic stimulation measures in older clinical populations

Purpose: Transcranial magnetic stimulation (TMS) is a versatile technique, capable of assessing cortical reactivity, intracortical inhibition/facilitation, and neuroplastic mechanisms within a single session. The goal of the present study is to directly assess the reproducibility of common TMS measures in older adults, including those with type-2 diabetes mellitus (T2DM), or Alzheimer’s disease (AD).