Facteurs Prédictifs De Complications Des Ponctions Transpariétales Thoraciques

Introduction. - CT-guided transthoracic core-needle biopsy (TTNB) is frequently used for the diagnosis of lung nodules. The aim of this study is to describe TTNBs' complications and to investigate predictive factors of complications.Methods. - All consecutive TTNBs performed in three centers between 2006 and 2012 were included. Binary logistic regression was used for multivariate analysis.Results. - Overall, 970 TTNBs were performed in 929 patients. The complication rate was 34% (life-threatening complication in 6%). The most frequent complications were pneumothorax (29% included 4% which required chest-tube) and hemoptysis (5%). The mortality rate was 0.1% (n = 1). In multivariate analysis, predictive factor for a complication was small target size (AOR = 0.984; 95% CI [0.976-0.992]; P < 0.001). This predictive factor was also found for occurrence of life-threatening complication (AOR = 0.982; [0.965-0.999]; P = 0.037), of pneumothorax (AOR = 0.987; [0.978-0.995]; P = 0.002) and of hemoptysis (AOR = 0.973; [0.951-0.997]; P = 0.024).Conclusion. - One complication occurred in one-third of TTNBs. The proportion of life threatening complication was 6%. A small lesion size was predictive of complication occurrence. (C) 2016 Elsevier Masson SAS. All rights reserved.