Anti‐tumour necrosis factor α‐induced lupus erythematosus panniculitis

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY(2017)

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摘要
Anti-tumor necrosis factor alpha (TNFα) therapies are used with success in many chronic inflammatory diseases. A wide range of adverse events has been reported in patients receiving these agents1, including lichenoid eruptions, lupus-like syndrome1, 2 and psoriasiform eruptions3. Lupus erythematosus panniculitis (LEP) is a rare variant of cutaneous lupus erythematosus (CLE), which occurs approximately in 1%-3% of CLE. Here we report a case of a patient with rheumatoid arthritis (RA) treated with anti-TNFα that developed skin lesions clinically and pathologically compatible with LEP.This article is protected by copyright. All rights reserved.
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