GW26-e2189 MiR-21 Ameliorates Cerebral Ischemia/Reperfusion Injury via PI3K/Akt/GSK-3β Pathway

Qian Wang,Jianbing Zhu,Lei Zhang, Huiying Xie, Chuanyong Wu,Xiaohui Liang,Shujun Xu,Jiatao Lou

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2015）

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Abstract

miR-21 has been reported to be a strong anti-apoptosis factor as shown that it suppresses OGD-induced apoptotic cell death and protects against ischemic neuronal death. However, the underlying mechanisms of miR-21 regulating cerebral ischemic/reperfusion (I/R) injury are not entirely understood. The

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Key words

ischemia/reperfusion injury

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