Long Term Follow-Up Of "Full Metal Jacket" Of De Novo Coronary Lesions With New Generation Zotarolimus-Eluting Stents
INTERNATIONAL JOURNAL OF CARDIOLOGY(2016)
Abstract
Background: Diffuse coronary artery disease treatment still remains a challenge for interventional cardiologists and cardiac surgeons. There are few data on full metal jacket (FMJ) stenting, especially with new-generation drug-eluting stents. We aimed to assess the efficacy and safety of FMJ with new-generation Zotarolimus-eluting stents (n-ZES).Methods and results: All patients who underwent FMJ with n-ZES (>= 60 mm stent length) in eleven Italian interventional centers participating in the Clinical Service r project were included in this analysis.The project population consisted of 120 patients and 122 lesions. Mean age was 67 +/- 10 years and 95 (79.2%) patients were male. A chronic total occlusion was present in 34 lesions (27.9%). The number of stents implanted per lesion was 2.9 +/- 0.8, and the diameter of the stents was 3.0 +/- 0.5 mm. Predilation and post-dilatation were performed in 107 (87.7%) and 92 (75.4%) patients, respectively.At 41 +/- 21 month follow-up there were 2 patients with subacute definite stent thrombosis, 6 patients (5.0%) had cardiac death and 5 patients (4.2%) had non-fatal myocardial infarction. Seven patients (5.8%) underwent clinically-driven target lesion revascularization. Fourteen patients (11.7%) had at least one major adverse cardiac event.Conclusion: The treatment of diffuse coronary artery disease with FMJ stenting with n-ZES appears to be effective and safe. Late and very-late ST does not seemto be an issue and the rate of restenosis and of major cardiac adverse events after more than 3-year follow-up is rather low. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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Key words
DES, Drug eluting stent, PCI, Full metal jacket, ZES
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