Vorinostat in refractory soft tissue sarcomas – Results of a multi-centre phase II trial of the German Soft Tissue Sarcoma and Bone Tumour Working Group (AIO)

Thomas Schmitt,Regine Mayer-Steinacker,Frank Mayer,Viktor Grünwald,Jochen Schütte,Jörg T. Hartmann,Bernd Kasper,Johannes Hüsing,Jacek Hajda,Gregor Ottawa,Gunhild Mechtersheimer,Gerd Mikus,Jürgen Burhenne,Lorenz Lehmann,Christoph E. Heilig,Anthony D. Ho,Gerlinde Egerer

European Journal of Cancer（2016）

引用 25|浏览35

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摘要

•First multi-centre trial on vorinostat in Soft Tissue Sarcoma.•Objective response to treatment was low.•A subgroup of patients experienced long-lasting disease stabilisation.

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关键词

Soft Tissue Sarcoma,Metastatic,Locally advanced,Vorinostat,Histone deacetylase-inhibition

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