Development and validation of a rapid LC–MS/MS method for simultaneous determination of netupitant and palonosetron in human plasma and its application to a pharmacokinetic study

Mingzhen Xu,Yang Ni,Shihong Li, Juan Du,Huqun Li,Ying Zhou,Weiyong Li,Hui Chen

Journal of Chromatography B（2016）

引用 7|浏览14

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摘要

•Firstly develope a rapid LC–MS/MS method for simultaneous determination of netupitant and palonosetron in human plasma.•Validate the LC–MS/MS method.•Apply the validated method to a pharmacokinetic study.

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关键词

Netupitant,Palonosetron,LC–MS/MS,Human plasma,Pharmacokinetics

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