Experimental Study on Effects of Yinchen Lidan Pian(茵陈利胆片) on Rabbits' Bacterial Cholecystitis

Objective: To explore the effects of Yinchen lidan pian on bacterial cholecystitis. Methods:Rabbits were injected Escherichia coli in gall bladder to build models of bacterial cholecystitis.. Experiment was divided into six groups,they were normal,model,positive and Yinchen lidan pian three dose groups,each group was given the corresponding medicine for 12 days. Rabbitsu0027 body temperature,WBC count and serum ALT and AKP activities were determined,taking rabbitsu0027 gall bladder to prepare tissue homogenate for determining SOD activity and MDA content. Results: To compare with model group,high dosage Yinchen lidan pian could lower rabbitsu0027 body temperature significantly and WBC count,decrease serum ALT and AKP activities,SOD activity of gall bladder tissue was increased and MDA content was reduced obviously. Conclusion: Yinchen lidan pian can effectively prevent and treat bacterial cholecystitis.