Unprecedented 3-O-methyl-3-C-trifluoromethyl-d-ribono- (and l-lyxono)-γ-lactones synthesized by nucleophilic trifluoromethylation of d-hexose-derived cyclic ketones

•Preparation of 3-CF3 glyconolactones by multi-step routes from d-glucose.•The introduction of CF3 group was achieved by nucleophilic trifluoromethylation.•The nucleophilic trifluoromethylation carried out by using Ruppert-Prakash reagent.