C-13β-ACYLOXYMILBEMYCINS, A NEW FAMILY OF MACROLIDES

Mark A. Maxell,Bernard F. Bishop,Patricia Bryce,Kenneth A. F. Oration,Hamida Kara,Robert A. Monday,Michael S. Pacey,David A. Perry,Yasuhiro Kojima,Hiroshi Maeda,Satoshi Nishiyama,Junsuke Tone,Liang H. Huang

The Journal of Antibiotics（1992）

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摘要

A family of novel milbemycins possessing C-13β-acyloxy substitution was produced by Streptomyces hygroscopicus ATCC 53718. These compounds were detected by HPLC diode array analysis and possess anthelmintic and ectoparasiticidal activity. The origin of the oxygen atom at C-13 is discussed.

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