beta-Phosphorus hyperfine coupling constant in nitroxides: 5. Solvent effect

Recently, we published the titration of water in organic solvents and conversely using this family of nitroxides (Org. Biomol. Chem. 2015 ASAP). In this article, we show that the a(beta,P) of persistent cyclic beta-phosphorylated nitroxides decreases with the normalized polarity Reichardt's constant E-T(N). Koppel-Palm and Kalmet-Abboud-Taft relationships were applied to get a deeper insight into the effects influencing a(N) and a(beta,P): polarity/polarizability, hydrogen bond donor property, and structuredness of the cybotactic region.