TNF-α is upregulated in T2DM patients with fracture and promotes the apoptosis of osteoblast cells in vitro in the presence of high glucose.

Cytokine(2016)

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摘要
•Cytokines and chemokines are upregulated in T2DM patients with bone fracture.•High glucose promotes TNF-α and IL-1β in MG-63 cells TNF-α promotes the apoptosis of osteoblast cells in the presence of high glucose.
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关键词
Bone fracture,TNF-α,T2DM,Apoptosis,Osteoblast cells,High glucose
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