TNF-α is upregulated in T2DM patients with fracture and promotes the apoptosis of osteoblast cells in vitro in the presence of high glucose.
Cytokine(2016)
摘要
•Cytokines and chemokines are upregulated in T2DM patients with bone fracture.•High glucose promotes TNF-α and IL-1β in MG-63 cells TNF-α promotes the apoptosis of osteoblast cells in the presence of high glucose.
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关键词
Bone fracture,TNF-α,T2DM,Apoptosis,Osteoblast cells,High glucose
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