Myeloperoxidase – ein neuer Marker zur Erforschung von Entzündungen?

Neutrophilic granulocytes, the most abundant immune cell type in the blood, are essential for the initiation as well as for the regulation and termination of acute inflammatory reactions. Thereby the enzyme myeloperoxidase (MPO) formed by these cells could be a key player. Thus a newly developed method for the quick purification of neutrophilic granulocytes from blood samples and a subsequent activity staining for MPO is presented which may contribute to a better understanding of the (patho-)physiological role of this enzyme.