Study of matrix effects for liquid chromatography–electrospray ionization tandem mass spectrometric analysis of 4 aminoglycosides residues in milk

Yuan Wang,Shaohui Li,Feifang Zhang,Yifeng Lu,Bingcheng Yang,Feng Zhang,Xinmiao Liang

Journal of Chromatography A（2016）

引用 41|浏览10

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摘要

•Matrix effect for aminoglycoside analysis in milk by LC–MS was explored.•Consecutive SPE pretreatment was used to reduce matrix effect.•Lower matrix effect was obtained by optimal strategies.

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关键词

Matrix effect,Aminoglycosides,Sample preparation,Consecutive SPE,Milk,LC–MS/MS

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