Radiomics signature: A potential and incremental predictor for EGFR mutation status in NSCLC patients, comparison with CT morphology

•Radiomics signature was a non-invasive predictor of EGFR mutant for NSCLC patients.•Radiomics signature had good predictive value to differentiate EGFR mutation group.•Radiomics signature outperformed clinical and CT morphological features.•Integrated model outweighed clinical models for predicting EGFR mutant.