Antikörper-Mikropatterns zur Analyse von Proteininteraktionen in Zellen

BIOspektrum(2018)

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摘要
The study of protein-protein and protein-ligand interactions at the cell surface is especially important for understanding many processes that are central to the life of the cell. Here, we present a novel two-hybrid assay based on antibody micropatterns that allows the visualization, measurement, and quantification of such interactions in the natural environment of the cell. We demonstrate the potential of our micropatterns with an immunological example.
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