Grapefruit Juice prolongs the QT Interval of Healthy Volunteers and Patients with Long QT syndrome.

Ehud Chorin,Aviram Hochstadt,Yoav Granot,Shafik Khoury,Arie Lorin Schwartz,Gilad Margolis,Rami Barashi,Dana Viskin,Eihab Ghantous,Michael Schnapper, Tal Mekori,Dana Fourey,Milton Ernesto Guevara-Valdivia,Manlio F Marquez,David Zeltzer,Raphael Rosso,Sami Viskin

Heart Rhythm（2019）

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摘要

Grapefruit juice, at doses tested, prolongs the QT interval. The effect is significant in healthy volunteers, larger in females and more so in patients with long QT syndrome.

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关键词

Adverse events,Drug-induced long QT syndrome,Proarrhythmia

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