KRAS mutations in tongue squamous cell carcinoma.

Yusuke Akagi,Tomoyasu Tachibana,Yorihisa Orita,Yuka Gion,Hidenori Marunaka,Takuma Makino,Kentaro Miki,Naoki Akisada,Tadashi Yoshino,Kazunori Nishizaki,Yasuharu Sato

Acta oto-laryngologica（2019）

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摘要

KRAS mutations are not associated with p16 expression in TC and may predict poor prognosis in TC patients. Further analysis of mutations in regions other than codons 12 and 13 of KRAS will be necessary to determine the relationship between KRAS mutations and prognosis of this disease.

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关键词

KRAS,p16 INK4a,tongue cancer

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