Study on urine metabolic profiling and pathogenesis of hyperlipidemia.

Liu Yang,Zhu Li,Yanqi Song,Yijia Liu,Huan Zhao,Yuechen Liu,Tianpu Zhang,Yu Yuan,Xuemeng Cai,Shuo Wang, Pengwei Wang,Shan Gao,Lin Li,Yubo Li,Chunquan Yu

Clinica Chimica Acta（2019）

引用 31|浏览9

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摘要

•Non-targeted metabolomics based on UPLC-Q-TOF/MS has been used and analyzed in positive and negative ionization modes.•The urine of 60 patients with hyperlipidemia and 60 normal controls has been studied.•To explore the pathogenesis and find new targets for treatment of hyperlipidemia by finding metabolic profiling.

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关键词

Hyperlipidemia,Metabolomics,Biomarkers,Pathogenesis,UPLC-Q-TOF/MS

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