Effects of Azadirachta indica seed kernel extracts on early erythrocytic schizogony of Plasmodium berghei and pro-inflammatory response in inbred mice

Annette Habluetzel,Barbara Pinto,Sofia Tapanelli, Judith Nkouangang,Michela Saviozzi,Giuseppina Chianese,Annalisa Lopatriello,Alain Rodrigue Tenoh,Rakiswendé Serge Yerbanga,Orazio Taglialatela-Scafati,Fulvio Esposito,Fabrizio Bruschi

Malaria Journal（2019）

引用 15|浏览35

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摘要

The effects of the ME on the parasite-host interactions appeared to be mouse strain-dependent, but also related to the ripening stage of the neem fruits, as only the unripe fruit seed kernel extracts displayed appreciable bioactivity.

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关键词

Azadirachta indica, Antimalarials, Plasmodium berghei, Inbred mice, Inflammation, Matrix metalloproteinase-9, Tumour necrosis factor

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